THE ROLE OF BIOMARKERS AND CLINICAL AND ANAMNESTIC FACTORS IN PRE-ECLAMPSIA

Preeclampsia is one of the most dangerous complications of pregnancy, being a significant cause of maternal and perinatal mortality. Modern methods of predicting this condition are based on the analysis of clinical and anamnestic data, as well as on the assessment of specific biomarkers. Further studies of pathogenesis and the development of optimal prognostic algorithms will help to improve the accuracy of identifying high-risk groups and make screening more effective and accessible. This paper analyzes the scientific literature on the problem of early diagnosis of preeclampsia. The key risk factors influencing the development of pathology, and modern hypotheses about the mechanisms of its occurrence are considered. Particular attention is paid to the role of biochemical markers in predicting the disease, as well as the most promising predictors and their combinations that can improve the quality of early detection of high-risk patients.