Naturally Dangerous: Kratom: Marketed without registration, risky for health

Kratom (Mitragyna speciosa) is a plant native to Southeast Asia, known for its stimulant and opioid-like effects. In Asian cultures, it has been used to relieve pain and help manage opioid withdrawal. In recent years, kratom has gained popularity in Western countries as an alternative to prescription opioids and as a recreational substance. However, its increasing use has raised concerns about its safety, including dependence, addiction, and toxicity. Additionally, various cases have been reported discussing the potential risks associated with kratom use and withdrawal. Below are two clinical cases that exemplify the risks linked to its consumption and the abrupt discontinuation of kratom, highlighting the need for regulation.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-13
DOI
https://doi.org/10.5281/zenodo.14867184
Primary Topic
Alkaloids: synthesis and pharmacology
Type
article
Field-Weighted Citation Impact
0.00
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article

Naturally Dangerous: Kratom: Marketed without registration, risky for health

Zenodo (CERN European Organization for Nuclear Research)
Alkaloids: synthesis and pharmacology
article

Naturally Dangerous: Kratom: Marketed without registration, risky for health

article en

Abstract

Kratom (Mitragyna speciosa) is a plant native to Southeast Asia, known for its stimulant and opioid-like effects. In Asian cultures, it has been used to relieve pain and help manage opioid withdrawal. In recent years, kratom has gained popularity in Western countries as an alternative to prescription opioids and as a recreational substance. However, its increasing use has raised concerns about its safety, including dependence, addiction, and toxicity. Additionally, various cases have been reported discussing the potential risks associated with kratom use and withdrawal. Below are two clinical cases that exemplify the risks linked to its consumption and the abrupt discontinuation of kratom, highlighting the need for regulation.

Zenodo (CERN European Organization for Nuclear Research)
Universidad Nacional de Colombia (CO)
Good health and well-being
Openalex Percentile: Top 45%
Alkaloids: synthesis and pharmacology
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