Anorectal Melanoma: A Rare Cause of Rectal Bleeding and Diagnostic Dilemma a Case Report

This case highlights the diagnostic challenges of anal canal malignant melanoma, a rare and aggressive tumor often misdiagnosed as hemorrhoids. A 54-year-old female presented with an anal mass and intermittent rectal bleeding for eight months. Initial misdiagnosis delayed proper evaluation until a biopsy and PET scan suggested advanced, unresectable anorectal melanoma, later confirmed by histopathology and immunohistochemistry (HMB-45 and Melan-A positive). A palliative colostomy was performed for symptom relief. This case emphasizes the importance of early diagnosis in patients over 40 with rectal bleeding and anal masses, as timely evaluation can improve management and outcomes, and also notifies the early aggressiveness of the tumour.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-26
DOI
https://doi.org/10.5281/zenodo.15421245
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Anorectal Melanoma: A Rare Cause of Rectal Bleeding and Diagnostic Dilemma a Case Report

Zenodo (CERN European Organization for Nuclear Research)
Cutaneous Melanoma Detection and Management
article

Anorectal Melanoma: A Rare Cause of Rectal Bleeding and Diagnostic Dilemma a Case Report

article en

Abstract

This case highlights the diagnostic challenges of anal canal malignant melanoma, a rare and aggressive tumor often misdiagnosed as hemorrhoids. A 54-year-old female presented with an anal mass and intermittent rectal bleeding for eight months. Initial misdiagnosis delayed proper evaluation until a biopsy and PET scan suggested advanced, unresectable anorectal melanoma, later confirmed by histopathology and immunohistochemistry (HMB-45 and Melan-A positive). A palliative colostomy was performed for symptom relief. This case emphasizes the importance of early diagnosis in patients over 40 with rectal bleeding and anal masses, as timely evaluation can improve management and outcomes, and also notifies the early aggressiveness of the tumour.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 39%
Cutaneous Melanoma Detection and Management
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