Development And Evaluation of Gel Containing Extract of Moringa Leaves for Tooth Ache

Toothache is a common dental issue typically caused by bacterial infections, inflammation, or dental caries. Although conventional treatments are effective, they can be costly and may induce side effects. With increasing interest in herbal alternatives, this study explores the development and evaluation of a gel containing Moringa oleifera leaf extract for toothache relief. The gel was formulated using hydroxypropyl methylcellulose (HPMC) as a gelling agent and ethanolic extraction to obtain active compounds. Physicochemical properties such as pH, viscosity, and spreadability were assessed for stability and usability. Antimicrobial activity against Streptococcus mutans and Porphyromonas gingivalis was evaluated using the agar diffusion method. In vitro anti-inflammatory assays and sensory-based analgesic evaluations confirmed the extract’s therapeutic potential. The results showed that the gel had stable properties, strong antimicrobial activity, and effective anti-inflammatory and analgesic effects. The formulation was found to be safe, cost-effective, and user-friendly, supporting its potential as a natural alternative for managing dental pain and infections.