A review study on pathogenesis, symptoms, diagnosis, and treatment options of chordoma

ABSTRACT:Cancers result from uncontrolled division of cells that disrupt the normal activity of organs. Cancer is classified according to the origin organ. Chordoma (notochordal sarcoma) is a slowly progressing tumor of the spine. These tumors may develop in any part of the spinal cord but mostly develop near the tail bone also called sacral tumors. The most common types of chordoma are cranial chordoma, sacral chordoma, and spinal chordoma. The common sites for this cancer are the sacrum, skull base, and spine. These are diagnosed in about 1 individual in 1 million people every year. These tumors develop in late age and demonstrate poor prognosis. Additionally, these tumors also create many challenges to treat. The most common ways to diagnose chordoma are biopsy, magnetic resonance imaging, and computed tomography imaging. In this review article, we have briefly discussed chordoma's pathophysiology, diagnosis, and treatment options. Keywords: Cancer; Chordoma; Chordoma Diagnosis; Chordoma Risk Factors; Chordoma Treatment