MODERN HEPATOPROTECTORS MECHANISMS AND CLINICAL EFFICACY

Hepatoprotectors are agents that safeguard the liver from damage caused by toxins, oxidative stress, and inflammatory processes. Modern hepatoprotective agents include a variety of natural and synthetic compounds, with significant focus on phytochemicals derived from plants. This review explores the mechanisms of action of these agents, including their antioxidant, anti-inflammatory, and antifibrotic properties. Furthermore, we examine their clinical efficacy, highlighting recent studies that validate their therapeutic potential. Despite encouraging preclinical data, more well-structured clinical trials are needed to establish their role in modern hepatology.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-21
DOI
https://doi.org/10.5281/zenodo.15484479
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
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article

MODERN HEPATOPROTECTORS MECHANISMS AND CLINICAL EFFICACY

Zenodo (CERN European Organization for Nuclear Research)
Drug-Induced Hepatotoxicity and Protection
article

MODERN HEPATOPROTECTORS MECHANISMS AND CLINICAL EFFICACY

article en

Abstract

Hepatoprotectors are agents that safeguard the liver from damage caused by toxins, oxidative stress, and inflammatory processes. Modern hepatoprotective agents include a variety of natural and synthetic compounds, with significant focus on phytochemicals derived from plants. This review explores the mechanisms of action of these agents, including their antioxidant, anti-inflammatory, and antifibrotic properties. Furthermore, we examine their clinical efficacy, highlighting recent studies that validate their therapeutic potential. Despite encouraging preclinical data, more well-structured clinical trials are needed to establish their role in modern hepatology.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 45%
Drug-Induced Hepatotoxicity and Protection
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MODERN HEPATOPROTECTORS MECHANISMS AND CLINICAL EFFICACY · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS