Exploring the Oncogenic Potential of Zinc Finger Protein 835 (ZNF835) in Cancer: Gene Regulation, Pathogenicity, and Diagnostic Applications through AI-Enhanced Immunohistochemistry

Zinc Finger Protein 835 (ZNF835) is a protein- coding gene involved in DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding. This gene plays a significant role in the regulation of transcription by RNA polymerase II and is implicated in various cancer-related processes. ZNF835 has been predicted to interact with oncogenes and microRNAs (miRs) associated with tumor growth, suggesting its potential role as an oncogene. Notably, specific SNPs in African American males may target ZNF835, increasing their predisposition to certain cancers. This research paper explores ZNF835’s functional roles, its potential as an oncogene through various molecular pathways, its interactions with transcription factors and miRs, and the application of immunohistochemistry (IHC) and artificial intelligence (AI) in predicting and diagnosing cancer.