A Clinical Study of Islanders to Determine Adverse Effects of Benzodiazepines and Mood-Related Memories on Memory Recall Performance

Benzodiazepines have shown to disrupt the positive effects of long term potentiation between cells on memory recall and learned associations. By differentiating the adverse long term effects of Alprazolam (long-term) and Triazolam (short-term), a better diagnosis may be administered to patients to mitigate any damage to the brain’s metacognition and memory recall ability. Further research has also shown that simply recalling specific memories that are associated with strong emotions will cause said emotions to be materialized in present time and influence future thoughts for a short period (approximately 10 minutes). The presence of happy emotions and sad emotions are of interest and are known to affect memory recall significantly, thereby driving the question, what are the effects on memory recall performance from benzodiazepines after being primed with a happy or sad memory? This clinical study would show if the mood of memories aiding or hindering memory recall are independent of other factors, if benzodiazepines effectiveness are not only reliant on a participant’s tolerance but also their mood, and finally the possibility of strengthening or worsening memory recall performance when presented together beyond the known response with the use of benzodiazepines or mood related memories on their own.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-09
DOI
https://doi.org/10.5281/zenodo.15369186
Primary Topic
Memory Processes and Influences
Type
article
Field-Weighted Citation Impact
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article

A Clinical Study of Islanders to Determine Adverse Effects of Benzodiazepines and Mood-Related Memories on Memory Recall Performance

Zenodo (CERN European Organization for Nuclear Research)
Memory Processes and Influences
article

A Clinical Study of Islanders to Determine Adverse Effects of Benzodiazepines and Mood-Related Memories on Memory Recall Performance

article en

Abstract

Benzodiazepines have shown to disrupt the positive effects of long term potentiation between cells on memory recall and learned associations. By differentiating the adverse long term effects of Alprazolam (long-term) and Triazolam (short-term), a better diagnosis may be administered to patients to mitigate any damage to the brain’s metacognition and memory recall ability. Further research has also shown that simply recalling specific memories that are associated with strong emotions will cause said emotions to be materialized in present time and influence future thoughts for a short period (approximately 10 minutes). The presence of happy emotions and sad emotions are of interest and are known to affect memory recall significantly, thereby driving the question, what are the effects on memory recall performance from benzodiazepines after being primed with a happy or sad memory? This clinical study would show if the mood of memories aiding or hindering memory recall are independent of other factors, if benzodiazepines effectiveness are not only reliant on a participant’s tolerance but also their mood, and finally the possibility of strengthening or worsening memory recall performance when presented together beyond the known response with the use of benzodiazepines or mood related memories on their own.

Zenodo (CERN European Organization for Nuclear Research)
University of California, Los Angeles (US), Activision Blizzard (United States) (US)
Openalex Percentile: Top 50%
Memory Processes and Influences
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