Development and Evaluation of Mouth Freshener Films Using HPMC by Film Casting Method

OFDFs are a new form of medicine that is preferred for children, older patients and people who have difficulties swallowing. In this study, OFDFs were independently developed and examined by solvent casting, checking for physicochemical, mechanical and other patient-centric properties. HPMC was used as the main polymer in all the films and the films additionally contained plasticizers and superdisintegrants. Characterization of the paper involved measuring its appearance, thickness, how smoothly it disintegrates, its weight, how it scatters, its strength, surface pH, folded endurance and how the paper feels. The tests discovered that the film was even in thickness and disintegrated soon after application. The tensile strength and ability to fold made the paper sturdy when used or handled. The movies did not change the pH and had a good mouthfeel which encourages patients to complete treatment. The check on the developed OFDFs demonstrates they follow the required standards of accuracy, do not lose potency and are accepted by patients. Other possibilities for the future are combining different polymers, merging nanotechnology to increase drug capacity and designing several-layer films for organized drug distribution. Moreover, conducting scale-up studies, testing over the long term and checking bioavailability in clinical settings can support the transformation to marketed products. The findings demonstrate that OFDFs could be a good choice over regular oral medicines, with more chances for new development in medicine for specific people.