Genetic Improvements in Aquaculture: The Impact of CRISPR/Cas9 Technology

The CRISPR/Cas9 system has revolutionized genetic research in aquaculture, offering efficient, precise, and low off-target gene editing capabilities. This technology has been applied to nearly 20 species. Key areas of research include enhancing growth by targeting genes like myostatin (mstn), improving disease resistance through modifications in Toll-like receptors, and ensuring reproductive confinement by creating sterile species. Additionally, CRISPR has been used to manipulate omega-3 fatty acid production and alter pigmentation for ornamental fish. These advancements highlight the potential of CRISPR/Cas9 in improving aquaculture productivity, health, and product quality.