Diffuse Thyroid Lipomatosis: 2 Case Reports

Diffuse thyroid lipomatosis is a rare entity characterized by infiltration of the thyroid gland by mature adipose tissue causing a marked increase in thyroid size. The pathogenesis is unclear. The presence of mature adipose tissue in the thyroid gland parenchyma is not expected. In this article, we report two cases of Diffuse Thyroid Lipomatosis. The patients were female and aged 68 and 54 years, respectively. Both patients presented with cervical swelling and ultrasound revealed enlarged thyroid gland in both patients. Microscopically, mature adipose tissue with diffuse infiltration between thyroid follicle cells was seen in both patients.