INFLUENCE OF POLYPHENOL EXTRACT, EXTRACTED FROM THE PLANT QUICE (CYDONIA OBLONG), ON THE mitoKATP-CHANNEL OF THE RAT'S LIVER

In this article, the effect of PF-4 polyphenol extracts isolated from quince (Сydonia oblong) on the ATP-dependent potassium channel in rat liver mitochondria was studied. In the experiments, PF-4 polyphenol extracts (5 μg/ml, 10 μg/ml, 15 μg/ml, 20 μg/ml) activated the ATP-inhibited mitoKATP channel. The obtained results make it possible to create drugs with membrane-active action of PF-4 polyphenol extract in the future.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-04
DOI
https://doi.org/10.5281/zenodo.15148322
Primary Topic
Species Distribution and Climate Change
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

INFLUENCE OF POLYPHENOL EXTRACT, EXTRACTED FROM THE PLANT QUICE (CYDONIA OBLONG), ON THE mitoKATP-CHANNEL OF THE RAT'S LIVER

Zenodo (CERN European Organization for Nuclear Research)
Species Distribution and Climate Change
article

INFLUENCE OF POLYPHENOL EXTRACT, EXTRACTED FROM THE PLANT QUICE (CYDONIA OBLONG), ON THE mitoKATP-CHANNEL OF THE RAT'S LIVER

article en

Abstract

In this article, the effect of PF-4 polyphenol extracts isolated from quince (Сydonia oblong) on the ATP-dependent potassium channel in rat liver mitochondria was studied. In the experiments, PF-4 polyphenol extracts (5 μg/ml, 10 μg/ml, 15 μg/ml, 20 μg/ml) activated the ATP-inhibited mitoKATP channel. The obtained results make it possible to create drugs with membrane-active action of PF-4 polyphenol extract in the future.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 42%
Species Distribution and Climate Change
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.