WAYS TO PREVENT SIDE EFFECTS OF NONSTEROIDAL DRUGS

Adverse effects of medications, particularly those affecting the kidneys and cardiovascular system, represent a significant global medical concern. Non-steroidal anti-inflammatory drugs (NSAIDs) are among the primary contributors to these complications, as they are one of the most widely used drug classes. The pharmacological action of NSAIDs involves inhibiting the synthesis of vasodilatory renal prostaglandins by deactivating the cyclooxygenase enzyme. This inhibition can result in vasomotor acute kidney injury, acute tubulointerstitial nephritis, chronic kidney disease, and other renal complications.