Emulsome: A Revolutionary Advancement in Pharmaceutical Delivery

Emulsome are emerging as a promising lipid-based nanocarriers system designed to address the challenges of delivering hydrophobic drugs. By combining the structural advantages of liposomes and emulsions, emulsome feature a solid lipid core enveloped by a phospholipid bilayer. This unique architecture enhances drug solubility, protects bioactive compounds from degradation, and enables controlled and targeted drug release. This review provides a comprehensive analysis of emulsome composition, preparation techniques, and physicochemical properties. It also explores their versatile applications in drug delivery, particularly for improving the bioavailability and therapeutic performance of poorly water-soluble drugs. Finally, key challenges and recent advancements are highlighted, offering insights into the future potential of emulsome in revolutionizing drug development.