Key Treatment, Principles, and Recent Updates in the Management of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) is a common indolent B-cell malignancy characterized by the accumulation of mature B lymphocytes in the blood, bone marrow, and lymphoid tissues. The management of CLL/SLL has evolved significantly in recent years, with advances in targeted therapies and novel immunotherapies. Chronic lymphocytic leukemia (CLL) is a type of cancer that affects white blood cells called lymphocytes. Lymphocytes are part of the immune system and help fight infections. In Chronic Lymphocytic Leukemia, the lymphocytes grow and accumulate abnormally, leading to various health issues.