What are the recommendations for deprescribing benzodiazepines in older adults with prolonged use?

Long-term use of benzodiazepines carries significant adverse effects, especially in older adults, such as cognitive impairment, increased risk of falls and fractures, drug dependence, and withdrawal syndrome upon discontinuation of treatment. Therefore, prolonged treatment with these medications should be avoided, especially in this population.Deprescribing benzodiazepines is a complex process that requires a specific strategy to minimize adverse effects and facilitate safe discontinuation of the medication. This report reviews the existing recommendations and evidence that guide the deprescription of benzodiazepines in older adults.