Incidence and Outcome of Adverse Reactions to Anti-Snake Venom in Envenomous Snake Bite Cases: A Cross-Sectional Study

Snakebite envenomation is a critical public health issue in tropical and subtropical regions, including India, where agricultural workers are predominantly affected. Anti-snake venom (ASV) is the primary treatment modality, yet it is associated with significant adverse drug reactions (ADRs), including anaphylaxis. This cross-sectional study evaluates the incidence and outcomes of ASV-related ADRs among envenomous snakebite cases in a tertiary care hospital in Thrissur, Kerala. Out of 85 patients admitted with snakebites, 50 were envenomated and administered ASV. ADRs were reported in 40% of these cases, with anaphylaxis occurring in 8%. This study highlights the need for improved ASV administration protocols and public health interventions to enhance safety and outcomes in snakebite management.