MORPHOLOGICAL CHANGES IN THE THYMU OF 33-38 WEEKS OF INFANTS WITH ANTENNATAL DEATH

Those who died from intrauterine infection in the antenatal period accounted for 78.2% of all infants and formed the basis of our study. Morphological developmental lags in the thymus gland are characterized by: the width of the cortical layer of the thymus, the very small area of the medullary layer, and the almost complete absence of mature lymphocytes. The main morphological substrate of these changes was the small size of the reticuloepithelial cells of the thymus cortex, the short and thick appearance of the desmasomas, the abundance of sparse fibrous structures connecting the spaces between the desmasomas, especially in the perivascular areas of the cortex, which also led to the functional impairment of the hematohistogenic barrier.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-12-09
DOI
https://doi.org/10.5281/zenodo.14328776
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
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article

MORPHOLOGICAL CHANGES IN THE THYMU OF 33-38 WEEKS OF INFANTS WITH ANTENNATAL DEATH

Zenodo (CERN European Organization for Nuclear Research)
Myasthenia Gravis and Thymoma
article

MORPHOLOGICAL CHANGES IN THE THYMU OF 33-38 WEEKS OF INFANTS WITH ANTENNATAL DEATH

article en

Abstract

Those who died from intrauterine infection in the antenatal period accounted for 78.2% of all infants and formed the basis of our study. Morphological developmental lags in the thymus gland are characterized by: the width of the cortical layer of the thymus, the very small area of the medullary layer, and the almost complete absence of mature lymphocytes. The main morphological substrate of these changes was the small size of the reticuloepithelial cells of the thymus cortex, the short and thick appearance of the desmasomas, the abundance of sparse fibrous structures connecting the spaces between the desmasomas, especially in the perivascular areas of the cortex, which also led to the functional impairment of the hematohistogenic barrier.

Zenodo (CERN European Organization for Nuclear Research)
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Myasthenia Gravis and Thymoma
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