STUDY OF SERUM ELECTROLYTES AND ANTIOXIDANTS IN WOMEN WITH PREMENSTRUAL SYNDROME AND WITHOUT PREMENSTRUAL SYNDROME

Background: Nowadays, PMS is becoming more common in younger people, particularly in urban areas. It is widely known that the typical menstrual cycle involves a coordinated sequence of hormonal changes. However, it is unclear whether the distribution of different electrolytes undergoes simultaneous or comparable alterations. Objectives: To estimate and compare serum electrolytes (sodium and potassium) and antioxidants (vitamin c and uric acid) in women with PMS and healthy controls. Materials and Methods: A total of 122 subjects were included in the study. This includes 61 with premenstrual syndrome and 61 without premenstrual syndrome in women (intern students, hospital staff, and non teaching staff and U.G. students) in the age group of 18- 40 years having regular menstrual cycles for the past 6 months. Patients with Psychiatric disorders, Ovarian dysfunction, Gynaecological disorders or any Serious physical illness where excluded from study. Results: We found statistically significant differences between the PMS and the control groups in the concentrations of antioxidants (vitamin C and uric acid) and blood electrolyte levels (sodium and potassium). Conclusion: Our study provides valuable insights into the biochemical alterations associated with PMS and calls for further research in this area to improve patient care and management.