Formulation And Evaluation Of Soft Medicated Jellies For Treatment Of Vitamin B12 Deficiency

An innovative kind of oral dosage is oral medicated jelly. There is a need to design such dose form in order to address challenges presented by juvenile and geriatric patients in administering standard dosage forms. It is especially good for people who have difficulty swallowing. Oral jelly may be readily chewed and dissolves in saliva without the need for water, giving it a unique form other than dose form. Patients are further drawn to its beauty and delicate texture, resulting in excellent patient acceptability. Jelly is a semisolid dosage form that is clear, non-greasy, and suitable for both internal and exterior usage. Its matrix contains a considerable quantity of water and resembles mucilage but has a jelly-like consistency. Since it is a mobile drug delivery method, it is employed as acute treatment. The preparation process of jelly involves heating and congealing a gelling agent in water. The jelly's physicochemical properties, such as appearance, stickiness, pH, viscosity spread ability, drug release, homogeneity of content, and stability tests, are assessed.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-08
DOI
https://doi.org/10.5281/zenodo.13731662
Primary Topic
Pharmacology and Nanomedicine Research
Type
article
Field-Weighted Citation Impact
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article

Formulation And Evaluation Of Soft Medicated Jellies For Treatment Of Vitamin B12 Deficiency

Zenodo (CERN European Organization for Nuclear Research)
Pharmacology and Nanomedicine Research
article

Formulation And Evaluation Of Soft Medicated Jellies For Treatment Of Vitamin B12 Deficiency

article en

Abstract

An innovative kind of oral dosage is oral medicated jelly. There is a need to design such dose form in order to address challenges presented by juvenile and geriatric patients in administering standard dosage forms. It is especially good for people who have difficulty swallowing. Oral jelly may be readily chewed and dissolves in saliva without the need for water, giving it a unique form other than dose form. Patients are further drawn to its beauty and delicate texture, resulting in excellent patient acceptability. Jelly is a semisolid dosage form that is clear, non-greasy, and suitable for both internal and exterior usage. Its matrix contains a considerable quantity of water and resembles mucilage but has a jelly-like consistency. Since it is a mobile drug delivery method, it is employed as acute treatment. The preparation process of jelly involves heating and congealing a gelling agent in water. The jelly's physicochemical properties, such as appearance, stickiness, pH, viscosity spread ability, drug release, homogeneity of content, and stability tests, are assessed.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 40%
Pharmacology and Nanomedicine Research
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Formulation And Evaluation Of Soft Medicated Jellies For Treatment Of Vitamin B12 Deficiency · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS