Utility and Accuracy of Frozen Section Examination for Uterine Tumors- A Cross Sectional Study

Introduction: Intraoperative frozen sections (IFS) play a vital role in guiding surgicalprocedures, especially in gynaecological oncology. The rapid diagnosis provided byfrozen sections allows surgeons to make real time decisions during surgery, which cansignificantly impact patient outcomes. It is a demanding task for pathologists, requiringkeen observation skills and the ability to make quick yet accurate assessments. Theinformation gleaned from frozen sections helps surgeons determine the extent of thesurgery needed and whether further interventions such as lymph node dissection, arenecessary. This approach enables a more precise and tailored treatment plan for eachpatient, improving overall care and potentially reducing the need for additionalsurgeries. Objectives: To compare the results of intraoperative frozen sectionexamination with the final histopathology report and assess its accuracy in diagnosinguterine tumors. Methods: After Institutional Ethics Committee approval, a crosssectional study was carried out on 10 frozen section specimens of uterine origin. Laterhistopathological evaluation was done. Both frozen section diagnosis andhistopathological diagnosis were compared to find out the accuracy of frozen sectionexamination. Results: Fromthe10 cases studied on frozen section, 5 cases werediagnosed as Endometrial adenocarcinoma. Others included 1 of Low gradeendometrial stromal sarcoma, 1 of Smooth muscle tumour of uncertain malignantpotential (STUMP) and 3 cases of Cellular leiomyoma. The diagnosis given on frozensection matched the final histopathological diagnosis in all the cases. Conclusion: Wefound that frozen section diagnosis in uterine tumors were accurate in all the cases westudied, because it matched the diagnosis given on subsequent histopathology. Hencefrozen section can be a useful tool for intraoperative diagnosis of uterine tumors.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-08-08
DOI
https://doi.org/10.5281/zenodo.13268010
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
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article

Utility and Accuracy of Frozen Section Examination for Uterine Tumors- A Cross Sectional Study

Zenodo (CERN European Organization for Nuclear Research)
Endometrial and Cervical Cancer Treatments
article

Utility and Accuracy of Frozen Section Examination for Uterine Tumors- A Cross Sectional Study

article en

Abstract

Introduction: Intraoperative frozen sections (IFS) play a vital role in guiding surgicalprocedures, especially in gynaecological oncology. The rapid diagnosis provided byfrozen sections allows surgeons to make real time decisions during surgery, which cansignificantly impact patient outcomes. It is a demanding task for pathologists, requiringkeen observation skills and the ability to make quick yet accurate assessments. Theinformation gleaned from frozen sections helps surgeons determine the extent of thesurgery needed and whether further interventions such as lymph node dissection, arenecessary. This approach enables a more precise and tailored treatment plan for eachpatient, improving overall care and potentially reducing the need for additionalsurgeries. Objectives: To compare the results of intraoperative frozen sectionexamination with the final histopathology report and assess its accuracy in diagnosinguterine tumors. Methods: After Institutional Ethics Committee approval, a crosssectional study was carried out on 10 frozen section specimens of uterine origin. Laterhistopathological evaluation was done. Both frozen section diagnosis andhistopathological diagnosis were compared to find out the accuracy of frozen sectionexamination. Results: Fromthe10 cases studied on frozen section, 5 cases werediagnosed as Endometrial adenocarcinoma. Others included 1 of Low gradeendometrial stromal sarcoma, 1 of Smooth muscle tumour of uncertain malignantpotential (STUMP) and 3 cases of Cellular leiomyoma. The diagnosis given on frozensection matched the final histopathological diagnosis in all the cases. Conclusion: Wefound that frozen section diagnosis in uterine tumors were accurate in all the cases westudied, because it matched the diagnosis given on subsequent histopathology. Hencefrozen section can be a useful tool for intraoperative diagnosis of uterine tumors.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 48%
Endometrial and Cervical Cancer Treatments
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