A Rare Case Report on Cervical Carcinosarcoma, Clinical Presentation and Treatment Outcome

Abstract Cervical carcinosarcoma (CCS) also known as malignant mixed mesodermal tumor (MMMT) is a rare aggressive biphasic tumor which has high grade epithelial and mesenchymal components. Carcinosarcomas occur most frequently in uterine corpus, can also arise in ovaries, cervix, fallopian tubes, vagina, peritoneum, and extra genital sites. The Cancer Genome Atlas (TCGA) data supports conversion and combination theories where carcinomatous cells convert themselves in sarcomatous via epithelial to mesenchymal transition. Currently there has been no consensus regarding survival, management and prognosis of CCS. Here we report a case of a perimenopausal female with abnormal uterine who was diagnosed preoperatively on biopsy as poorly differentiated carcinoma, was taken for radical hysterectomy and was diagnosed on final histopathology as carcinosarcoma of cervix.