FORMULATION AND EVALUATION OF VERAPAMIL HYDROCHLORIDE EMULGEL FOR TOPICAL DRUG DELIVERY

Topical drug delivery offers an alternative to oral and intravenous administration, often providing better patient compliance and localized action. This study aims to formulate a Verapamil Hydrochloride emulgel, a calcium channel blocker primarily used to treat hypertension, and evaluate its effectiveness for diffusion through the skin. Emulgels combine the benefits of gels and emulsions, creating an ideal vehicle for poorly water-soluble drugs. Various parameters, including pH, drug content, in vitro drug release, and swelling index, were evaluated to determine the optimal formulation for transdermal delivery.