The soluble form of Tim-3 (sTim-3) aggravates CD8+ T cell exhaustion and resistance to anti-PD-1 immunotherapy through CEACAM-1
The following text describes files named "fpkm.anno".This csv data file contains differential gene expression patterns and gene signatures. | File name | File category | File type | Experiment or Analysis | Related to Figure(s) | Description | fpkm.anno | sTim3-vs-MOCK.csv | fpkm list | RNA sequencing of sTim3 treated CD8+T cells and Mock CD8+T cells | Fig5 | Differential expression results table for sTim3-treated CD8+T cells vs Mock CD8+T cells**Plain text (.csv) files can be interpreted as follows:**Stand-alone plain csv files, containing a csv file of differential expression results, for all genes. These tables can be used to search for results of genes not discussed in the text. Tables contain the following information (in columns) for each gene (in rows):fpkm.anno.csv result file description: name = ID of the gene sTim3-1,2,3 = sTim3-1,2,3-Experimental group in the article Mock-1,2,3 = Mock-1,2,3-Control group in the article GeneName = Name of the gene Biotype = gene type Positon = coordinates of genes NR:Seq-id = optimal comparison results between genes and NR database NR:Score = the score of gene comparison with NR database NR:Evalue = The Evalue value of genes compared with the NR database NR: Description = Function description of the gene in the NR database NT:Seq-id = optimal comparison results between genes and NT database NT:Score = comparison score between gene and NT database NT:Evalue = The Evalue value of genes compared with NT database NT: Description = Description: Function description of the gene in the NT database Uniprot:UniprotKB-AC = optimal comparison results between genes and Uniprot database Uniprot:Score = the score of genes compared with Uniprot database Uniprot: Evalue = The Evalue value of genes compared with Uniprot database Uniprot: Description = Function description of the gene in niprot database COG:gene =gene name in the COG database compare COG:Score = the score compared with the COG database COG:Eval = comparison with the COG database Evalue value COG:num = gene ID in the COG database compared Pfam:pfam_ID = gene ID of the protein family Pfam compared Pfam:pfam_Name = the gene name of the protein family Pfam compared Pfam:pfam_Description = Functional description of the protein family Pfam compared GO:biological_process = Annotated GO Term describing the biological process GO:cellular_component = Annotated GO Term describing cell components GO:molecular_function = the commented GO Term describing the molecular function KEGG:KO = the ID in KEGG commented to KEGG:Description = Function description in KEGG
Institutions
- Shandong University (CN)
- Chinese Academy of Sciences (CN)
- Zhoushan Hospital (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2024-08-30
- DOI
- https://doi.org/10.5281/zenodo.12741081
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00