Exploring Microsponge Technology: Applications Beyond Topical Drug Delivery
An ultra-innovative drug delivery method called Microsponge has been developed for oral or topical use. Entrapped medicinal compounds are shielded from physical and environmental deterioration by microsponges, which are porous microspheres composed of polymer and biologically inert. Microsponge sizes range from 5 to 300 μm in diameter. Microsponge delivery systems (MDS) have been the subject of several recent developments for the controlled release of medications onto the epidermis with the guarantee that the drug stays mostly localized and does not significantly enter the systemic circulation. MDS is a unique technology for the controlled release of topical medications. It is also utilized for the administration of oral medications and biopharmaceuticals, which include peptides, proteins, and DNA-based therapies. It is made up of microporous beads with diameters ranging from 10 to 25 microns, which are versatile enough to ensnaffle a variety of active substances. This review article includes information on patents and commercially available formulations along with techniques of preparation, release mechanism, characterisation, and uses of microsponge delivery systems.
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2024-12-15
- DOI
- https://doi.org/10.5281/zenodo.14487858
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00