Evaluation of Tzanakis Score in Acute Appendicitis among Indian Patients

Aim: This study is aimed to detect the efficacy of Tzanakis scoring system in diagnosing acute appendicitis in our set up using histopathology as the gold standard. Materials and Methods: This cross-sectional validation study was carried out in ESIC Medical College & Hospital, Kalaburagi from October 2023 to October 2024, after approval from the Ethics Committee of the Hospital. The study included all adult patients of either gender who presented with clinical findings suggestive of acute appendicitis, who were assigned Tzanakis score pre-operatively and who subsequently underwent emergency appendicectomy with histological examination of the resected specimens. Result: Sensitivity of Tzanakis score in diagnosing acute appendicitis was 91.3%, specificity 57.14%, positive predictive value 93.33%, negative predictive value 50% and diagnostic accuracy was 86.79%. The area under the curve (AUC) of the receiver operator characteristic (ROC) curve for the Tzanakis scoring system was 0.742, with a standard error of 0.083, 95% confidence interval- 0.579 – 0.906, p value = 0.004. Conclusion: This study concluded that the Tzanakis scoring system is acceptable for diagnosing acute appendicitis.