Synthesis, Characterization And In-Silico Studies Of Novel Thiazolidine Analogues And Their Assessment As Potential Dpp4 Inhibitors

In this study, four Schiff bases (HSB-1 to HSB-4) were synthesized via condensation reactions between aldehydes and primary amines, which served as intermediates for the subsequent synthesis of four Thiazolidine derivatives (T-1 to T-4) through cyclization with cysteine. Structural elucidation of these compounds was confirmed using advanced spectroscopic techniques, including NMR

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-10-25
DOI
https://doi.org/10.5281/zenodo.13990168
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00
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article

Synthesis, Characterization And In-Silico Studies Of Novel Thiazolidine Analogues And Their Assessment As Potential Dpp4 Inhibitors

Zenodo (CERN European Organization for Nuclear Research)
Single-cell and spatial transcriptomics
article

Synthesis, Characterization And In-Silico Studies Of Novel Thiazolidine Analogues And Their Assessment As Potential Dpp4 Inhibitors

article en

Abstract

In this study, four Schiff bases (HSB-1 to HSB-4) were synthesized via condensation reactions between aldehydes and primary amines, which served as intermediates for the subsequent synthesis of four Thiazolidine derivatives (T-1 to T-4) through cyclization with cysteine. Structural elucidation of these compounds was confirmed using advanced spectroscopic techniques, including NMR

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 59%
Single-cell and spatial transcriptomics
DOIOpen Access PDFOpenAlex
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Synthesis, Characterization And In-Silico Studies Of Novel Thiazolidine Analogues And Their Assessment As Potential Dpp4 Inhibitors · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS