Nasal Mucosal Leishmaniasis: A Case Report

Leishmaniasis is a parasitic disease with various forms, including visceral, cutaneous, and mucocutaneous types. In Morocco, cutaneous leishmaniasis is endemic, while mucocutaneous leishmaniasis (MCL), particularly nasal mucosal involvement, is rare. We report a case of nasal mucosal leishmaniasis in a 55-year-old immunocompetent woman with a 2-year history of a treatment-resistant papular lesion. Diagnosis was confirmed after biopsy, revealing Leishman bodies, and the patient was successfully treated with intramuscular meglumine antimoniate, showing significant improvement within the first week. Nasal mucosal leishmaniasis is exceptionally uncommon and responds well to standard treatment in immunocompetent patients. Early diagnosis and appropriate treatment are crucial for a favorable outcome, even in atypical cases like this one.