CA074Me attenuates titanium nanoparticle-induced osteolysis via inhibition of macrophage NLRP3 inflammasome activation and osteoclast differentiation

Objectives: Aseptic loosening due to peri-implant osteolysis remains the leading cause of long-term implant failure. Increasing evidence suggests that wear debris-induced NLRP3 inflammasome activation in macrophages and subsequent inflammatory osteoclast activation play an essential role in the progression [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2024-10-21
DOI
https://doi.org/10.3205/24dkou156
Primary Topic
Species Distribution and Climate Change
Type
article
Field-Weighted Citation Impact
0.00
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article

CA074Me attenuates titanium nanoparticle-induced osteolysis via inhibition of macrophage NLRP3 inflammasome activation and osteoclast differentiation

German Medical Science (German Research Foundation)
Species Distribution and Climate Change
article

CA074Me attenuates titanium nanoparticle-induced osteolysis via inhibition of macrophage NLRP3 inflammasome activation and osteoclast differentiation

article en

Abstract

Objectives: Aseptic loosening due to peri-implant osteolysis remains the leading cause of long-term implant failure. Increasing evidence suggests that wear debris-induced NLRP3 inflammasome activation in macrophages and subsequent inflammatory osteoclast activation play an essential role in the progression [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
University Hospital Bonn (DE)
Openalex Percentile: Top 67%
Species Distribution and Climate Change
DOIOpen Access PDFOpenAlex
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CA074Me attenuates titanium nanoparticle-induced osteolysis via inhibition of macrophage NLRP3 inflammasome activation and osteoclast differentiation · German Medical Science (German Research Foundation) (2024) | TGRS Research Map | TGRS