Thermonuclease NucA makes Staphylococcus aureus highly pathogenic for septic arthritis
Objectives: Gram-positive Staphylococcus aureus are the most common cause for septic arthritis in humans. The mature thermonuclease Nuc1 (known as NucA) is secreted by S. aureus and plays an important role in its virulence. NucA degrades extracellular DNA and RNA, and thus contributes to bacterial escape [for full text, please go to the a.m. URL]
Institutions
- Goethe University Frankfurt (DE)
- BG Klinik Tübingen (DE)
- University of Tübingen (DE)
- University of Gothenburg (SE)
Publication Details
- Journal
- German Medical Science (German Research Foundation)
- Published
- 2024-10-21
- DOI
- https://doi.org/10.3205/24dkou516
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00