The role of PTHrP for the mechanoresponse of MSC-derived chondrocytes

Objectives: Mesenchymal stem cell (MSC)-based regenerative therapies hold great promise for the repair of articular cartilage defects. However, it is unclear how to generate MSC-derived neocartilage that can adequately respond to mechanical loading, which appears to be critical for their therapeutic [for full text, please go to the a.m. URL]

Institutions

Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2024-10-21
DOI
https://doi.org/10.3205/24dkou537
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

The role of PTHrP for the mechanoresponse of MSC-derived chondrocytes

German Medical Science (German Research Foundation)
Osteoarthritis Treatment and Mechanisms
article

The role of PTHrP for the mechanoresponse of MSC-derived chondrocytes

article en

Abstract

Objectives: Mesenchymal stem cell (MSC)-based regenerative therapies hold great promise for the repair of articular cartilage defects. However, it is unclear how to generate MSC-derived neocartilage that can adequately respond to mechanical loading, which appears to be critical for their therapeutic [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Heidelberg University (DE), University Hospital Heidelberg (DE)
Openalex Percentile: Top 47%
Osteoarthritis Treatment and Mechanisms
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The role of PTHrP for the mechanoresponse of MSC-derived chondrocytes · German Medical Science (German Research Foundation) (2024) | TGRS Research Map | TGRS