Stimulation of the reparative activities in human chondral defects via alginate hydrogel-guided rAAV sox9 and TGF- β gene delivery

Objectives: Recombinant adeno-associated virus gene vectors (rAAV) are promising vehicles to treat focal cartilage defects when delivered via biomaterials [ref:1]. The objective was to test whether rAAV carrying the reparative sox9 and TGF-β genes in an alginate hydrogel can stimulate [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2024-10-21
DOI
https://doi.org/10.3205/24dkou536
Primary Topic
Research Data Management Practices
Type
article
Field-Weighted Citation Impact
0.00
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article

Stimulation of the reparative activities in human chondral defects via alginate hydrogel-guided rAAV sox9 and TGF- β gene delivery

German Medical Science (German Research Foundation)
Research Data Management Practices
article

Stimulation of the reparative activities in human chondral defects via alginate hydrogel-guided rAAV sox9 and TGF- β gene delivery

article en

Abstract

Objectives: Recombinant adeno-associated virus gene vectors (rAAV) are promising vehicles to treat focal cartilage defects when delivered via biomaterials [ref:1]. The objective was to test whether rAAV carrying the reparative sox9 and TGF-β genes in an alginate hydrogel can stimulate [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Universitätsklinikum des Saarlandes (DE)
Openalex Percentile: Top 40%
Research Data Management Practices
DOIOpen Access PDFOpenAlex
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Stimulation of the reparative activities in human chondral defects via alginate hydrogel-guided rAAV sox9 and TGF- β gene delivery · German Medical Science (German Research Foundation) (2024) | TGRS Research Map | TGRS