3D spheroid culture of chondrocytes to study the interaction of cells at the chondro-osseous border of enchondral ossification dependent on Syndecan-1

Objectives: Syndecan-1 regulates inflammatory responses, controls cell migration during wound healing, and stabilizes endothelial cell-cell junctions [ref:1]. By binding and producing growth factors, it also helps to control endothelial cell proliferation and differentiation [ref:2]. [for full text, please go to the a.m. URL]