[Comment] Robotic surgery is associated with a decreased risk of circumferential resection margin positivity compared with conventional laparoscopic surgery in patients with rectal cancer undergoing mesorectal excision: a systematic review and meta-a

[Objective] To investigate whether robotic surgery (RS) decreases the risk of circumferential resection margin(CRM) positivity compared with conventional laparoscopic surgery (LS) in patients with rectal cancer (RC) undergoing mesorectal excision (ME). [Background] Although it is well known that CRM positivity affects postoperative outcomes in patients with RC undergoing ME, few studies have investigated whether RS is superior to conventional LS for the risk of CRM positivity. [Methods] We performed a comprehensive electronic search of the literature up to December 2022 to identify studies that compared the risk of CRM positivity between patients with RC undergoing robotic and conventional laparoscopic surgery. A meta-analysis was performed using random-effects models to calculate risk ratios (RR) and 95% confidence intervals (CI ), and heterogeneity was analyzed using I2 statistics. [Results] Eighteen studies, consisting of 4 randomized controlled trials (RCTs) and 14 propensity score matching (PSM) studies, involved a total of 9,203 patients with RC who underwent ME were included in this meta-analysis. The results demonstrated that RS decreased the overall risk of CRM positivity (RR, 0.82; 95%CI, 0.73-0.92; P＝0.001; I2＝0%) compared with conventional LS. Results of a metaanalysis of the 4 selected RCTs also showed that RS decreased the risk of CRM positivity (RR, 0.62; 95%CI, 0.43-0.91;P＝0.01; I2＝0%) compared with conventional LS. [Conclusions] This meta-analysis revealed that RS is associated with a decreased risk of CRM positivity compared with conventional LS in patients with RC undergoing ME.