TIME TO STABILIZATION AND ITS PREDICTORS AMONG 6 TO 59 MONTHS CHILDREN ADMITTED WITH SEVERE ACUTE MALNUTRITION TO SELECTED TERTIARY HOSPITALS IN WESTERN OROMIA, ETHIOPIA: RETROSPECTIVE COHORT STUDY.

ADVISORS MR. TESFAYE ABERA (MSc, ASS’T PROFESSOR). Background: Due to their fragile physiologic functions, over 65 percent of deaths from complicated severe acute malnutrition occur in the first week of treatment, primarily due to medical complications. To reduce this, early stabilization is crucial, and there is limited evidence regarding stabilization time in Ethiopia.<br> Objective: To assess time to stabilization and its predictors among 6 to 59 months old children admitted with severe acute malnutrition to selected hospitals in Western Oromia from January 2020 to December 2024.<br> Method: A retrospective cohort study was conducted from January 20 to february 29, 2025 on 543 sampled children selected by a simple random sampling from severely malnourished children admitted to three selected hospitals in Western Oromia between January 2020 and December 2024. After collecting data using kobotoolbox, it was exported to STATA version 17 for analysis. Kaplan Meier curve and log-rank test were used to estimate the stabilization rate and presence of statistically significant difference in survival and hazard rate between a categories of explanatory variables. Proportional hazard assumption was checked using schoenfeld residual test and log-log survival curve. After performing model comparison, Weibull model was selected and variable with p&lt;0.25 on bi-variate regression was selected for multivariable weibull regression. Estimating adjusted hazard ratio with their respective 95% confidence interval, P-value of less than 0.05 was used to declare statistically significant association with stabilizing time.<br> Result: Over 5600 child-days of observation, the median time to stabilize from severe acute malnutrition was 11 days, with 86.39% rate of stabilization and 86.6/1000 incidence of stabilization (95% CI: (74.45 - 89.44)). Immunization status (AHR: 0.66, 95 CI (0.54-0.8)), pneumonia (AHR: 2.17, 95 CI (1.74-2.70)), hospital acquired infections (AHR: 1.34 95CI (1.09-1.65)) and vitamin A supplementation (AHR: 0.61, 95CI (0.49-0.77)) were predictors of

Publication Details

Journal
National Academic Digital Repository of Ethiopia
Published
2025-07-13
DOI
https://doi.org/10.20372/nadre:14864
Primary Topic
Child Nutrition and Water Access
Type
article
Field-Weighted Citation Impact
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article

TIME TO STABILIZATION AND ITS PREDICTORS AMONG 6 TO 59 MONTHS CHILDREN ADMITTED WITH SEVERE ACUTE MALNUTRITION TO SELECTED TERTIARY HOSPITALS IN WESTERN OROMIA, ETHIOPIA: RETROSPECTIVE COHORT STUDY.

National Academic Digital Repository of Ethiopia
Child Nutrition and Water Access
article

TIME TO STABILIZATION AND ITS PREDICTORS AMONG 6 TO 59 MONTHS CHILDREN ADMITTED WITH SEVERE ACUTE MALNUTRITION TO SELECTED TERTIARY HOSPITALS IN WESTERN OROMIA, ETHIOPIA: RETROSPECTIVE COHORT STUDY.

article en

Abstract

ADVISORS MR. TESFAYE ABERA (MSc, ASS’T PROFESSOR). Background: Due to their fragile physiologic functions, over 65 percent of deaths from complicated severe acute malnutrition occur in the first week of treatment, primarily due to medical complications. To reduce this, early stabilization is crucial, and there is limited evidence regarding stabilization time in Ethiopia.<br> Objective: To assess time to stabilization and its predictors among 6 to 59 months old children admitted with severe acute malnutrition to selected hospitals in Western Oromia from January 2020 to December 2024.<br> Method: A retrospective cohort study was conducted from January 20 to february 29, 2025 on 543 sampled children selected by a simple random sampling from severely malnourished children admitted to three selected hospitals in Western Oromia between January 2020 and December 2024. After collecting data using kobotoolbox, it was exported to STATA version 17 for analysis. Kaplan Meier curve and log-rank test were used to estimate the stabilization rate and presence of statistically significant difference in survival and hazard rate between a categories of explanatory variables. Proportional hazard assumption was checked using schoenfeld residual test and log-log survival curve. After performing model comparison, Weibull model was selected and variable with p&lt;0.25 on bi-variate regression was selected for multivariable weibull regression. Estimating adjusted hazard ratio with their respective 95% confidence interval, P-value of less than 0.05 was used to declare statistically significant association with stabilizing time.<br> Result: Over 5600 child-days of observation, the median time to stabilize from severe acute malnutrition was 11 days, with 86.39% rate of stabilization and 86.6/1000 incidence of stabilization (95% CI: (74.45 - 89.44)). Immunization status (AHR: 0.66, 95 CI (0.54-0.8)), pneumonia (AHR: 2.17, 95 CI (1.74-2.70)), hospital acquired infections (AHR: 1.34 95CI (1.09-1.65)) and vitamin A supplementation (AHR: 0.61, 95CI (0.49-0.77)) were predictors of

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TIME TO STABILIZATION AND ITS PREDICTORS AMONG 6 TO 59 MONTHS CHILDREN ADMITTED WITH SEVERE ACUTE MALNUTRITION TO SELECTED TERTIARY HOSPITALS IN WESTERN OROMIA, ETHIOPIA: RETROSPECTIVE COHORT STUDY. · National Academic Digital Repository of Ethiopia (2025) | TGRS Research Map | TGRS