Learning from end-of-life injectable medication patient safety incidents in the community: a mixed-methods analysis.

BACKGROUND: Processes to implement injectable end-of-life symptom control medications in the community are complex and can have an adverse impact on patient safety. Recurring patient safety incident types and their contributory factors remain underrecognised, inhibiting system-wide learning. AIM: To understand injectable end-of-life symptom control medication incidents, their contributory factors, the impact on patients/families, and identify priority areas for improving safe, effective, and timely care. DESIGN AND SETTING: Mixed-methods analysis of nationally reported injectable medication patient safety incidents involving adults in the community in England and Wales between 2017 and 2022. METHOD: A stratified random sample of 2150 incidents from the National Reporting and Learning System were screened for eligibility. Incidents that involved end-of-life injectable medications in the community were included and analysed. Deductive coding was undertaken to classify incident types, the contributory factors involved, the impact on the patient, and harm severity. An iterative thematic analysis was then conducted to identify patterns between recurring incident types and contributory factors. RESULTS: In total, 419 patient safety reports detailed injectable medication-related patient safety incidents: 59.7% (n = 250) of incidents described harm to patients. Frequently reported patient safety incidents included: medication administration issues (49.2%, n = 206); delayed and inadequate assessments (10.3%, n = 43); and prescription issues (8.6%, n = 36). Incidents often involved multiple services and delays. Recurrent, and often interacting, contributory factors included inadequate continuity of care, distractions and mistakes, poor equipment design, and insufficient staffing levels. CONCLUSION: Interventions to improve injectable end-of-life symptom control care should focus on ensuring timely access to assessments and prescriptions, enhancing continuity of care, and mechanisms to ensure rapid visits to administer medication.

Publication Details

Journal
Apollo (University of Cambridge)
Published
2025-08-07
DOI
https://doi.org/10.17863/cam.120535
Primary Topic
Pharmaceutical Practices and Patient Outcomes
Type
article
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article

Learning from end-of-life injectable medication patient safety incidents in the community: a mixed-methods analysis.

Apollo (University of Cambridge)
Pharmaceutical Practices and Patient Outcomes
article

Learning from end-of-life injectable medication patient safety incidents in the community: a mixed-methods analysis.

article en

Abstract

BACKGROUND: Processes to implement injectable end-of-life symptom control medications in the community are complex and can have an adverse impact on patient safety. Recurring patient safety incident types and their contributory factors remain underrecognised, inhibiting system-wide learning. AIM: To understand injectable end-of-life symptom control medication incidents, their contributory factors, the impact on patients/families, and identify priority areas for improving safe, effective, and timely care. DESIGN AND SETTING: Mixed-methods analysis of nationally reported injectable medication patient safety incidents involving adults in the community in England and Wales between 2017 and 2022. METHOD: A stratified random sample of 2150 incidents from the National Reporting and Learning System were screened for eligibility. Incidents that involved end-of-life injectable medications in the community were included and analysed. Deductive coding was undertaken to classify incident types, the contributory factors involved, the impact on the patient, and harm severity. An iterative thematic analysis was then conducted to identify patterns between recurring incident types and contributory factors. RESULTS: In total, 419 patient safety reports detailed injectable medication-related patient safety incidents: 59.7% (n = 250) of incidents described harm to patients. Frequently reported patient safety incidents included: medication administration issues (49.2%, n = 206); delayed and inadequate assessments (10.3%, n = 43); and prescription issues (8.6%, n = 36). Incidents often involved multiple services and delays. Recurrent, and often interacting, contributory factors included inadequate continuity of care, distractions and mistakes, poor equipment design, and insufficient staffing levels. CONCLUSION: Interventions to improve injectable end-of-life symptom control care should focus on ensuring timely access to assessments and prescriptions, enhancing continuity of care, and mechanisms to ensure rapid visits to administer medication.

Apollo (University of Cambridge)
No poverty
Openalex Percentile: Top 45%
Pharmaceutical Practices and Patient Outcomes
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