Showing how MOR₅₀ is calculated for all antibiotic/species combinations.

The points represent the mean and standard deviation in cell area across repeats. The size of the error bars is large, as they capture the variation in cell size caused by the cell cycle. The MOR₅₀ threshold is halfway between the area with no antibiotic present and the maximum area change and is shown as a horizontal line. The cell MIC is where the area curve first crosses this threshold. This corresponds very closely with the IC₅₀ point as determined by the growth rate, represented by the vertical grey line. The plots for <i>E.coli</i> with ciprofloxacin and vancomycin are also presented in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012924#ppat.1012924.g007" target="_blank">Fig 7</a> and are included here for completeness. (PDF)