Differential Expression of 18 Male Samples, 18 mf Samples, 9 Female Samples in Group 1, and 9 Female Samples in Group 2.

<p>The dendrogram at the top of the heatmap was generated using pvclust. The red values are approximately unbiased (au) and the green are the bootstrap support (bp) values, both of which are generated by pvclust. The values shown are for illustrative purposes. The samples included are select adult male samples, microfilariae, and from the two groups of adult females. The heatmap uses a z-score normalization of log2(TPM) values for the 8, 697 differentially expressed genes. The legend at the top is broken into three sections: project color, if the sample was drug treated, and sample life stage. The left hand legend is broken into two sections: the outer section denotes the WGCNA cluster and the inner section denotes if cluster matches the main or inverse WGCNA cluster expression pattern. Samples were labeled with first author, title, and bioproject from [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012511#pntd.0012511.ref019" target="_blank">19</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012511#pntd.0012511.ref020" target="_blank">20</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012511#pntd.0012511.ref023" target="_blank">23</a>].</p> <p>(PDF)</p>