Recombination intermediates of CO events.

<p><b>A)</b> DSBR CO resolution. If SNP density is not high enough, hDNA tracts are missed (no strand transfer, <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s011" target="_blank">S11A Fig</a></b>). If SNP density is high enough, hDNA tracts are detected (two-sided unidirectional, <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s011" target="_blank">S11E Fig</a></b>). <b>B)</b> DSBR CO resolution resulting in full conversion (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s011" target="_blank">S11B Fig</a>). Both ends are processed. Short hDNA tracts not picked by the SNP density. <b>C)</b> DSBR CO resolution. Asymmetry in the positioning of the two HJ with respect to the initiating DSB event yeilding asymmetric hDNA tract (one long one short) (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s011" target="_blank">S11C Fig</a></b>). The short hDNA tract is not detected due to low SNP density. There are many complex combinations of events that can give rise to one-sided bidirectional transfer (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s011" target="_blank">S11D Fig</a></b>), so this had been omitted. <b>D)</b> Two-sided bidirectional event caused by two double-strand breaks, resulting in two-sided bidirectional transfer (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s011" target="_blank">S11F Fig</a></b>).</p> <p>(PDF)</p>