Recombination intermediates of NCO events.

<p><b>A)</b> Full conversion. The short hDNA tracts near the edges of the gap escape detection due to SNP density (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s009" target="_blank">S9A Fig</a></b>). <b>B)</b> Synthesis dependent strand annealing (SDSA). Results in a one-sided NCO (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s009" target="_blank">S9B Fig</a></b>) or one-sided + patch if there is a nick translation within the converted strand of an hDNA tract (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s009" target="_blank">S9C Fig</a></b>). <b>C)</b> Double SDSA. Results in a two-sided NCO (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s009" target="_blank">S9D Fig</a></b>) or two-sided + patch if there is a nick translation within the converted strand of an hDNA tract (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s009" target="_blank">S9E Fig</a></b>). Can also arise from dHJ dissolution and nicked dHJ disassembly. <b>D)</b> DSB repair with NCO resolution resulting in an NCO that affects two non-sister chromatids (<b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011485#pgen.1011485.s009" target="_blank">S9F Fig</a></b>).</p> <p>(PDF)</p>