CUT&Tag results from the two additional CENP-A replicates (top 2 row) and the IgG negative control (third row) and the mappability score (bottom row) for each centromere in <i>D</i>.

<p><i>simulans</i>. The y-axis represents the normalized CENP-A or IgG enrichment in RPM. Black and gray plotted lines represent the enrichment based on uniquely mapping and all reads (including multi-mappers), respectively. The black and gray tracks below each plot correspond to MACS2 peaks showing significantly enriched regions based on the uniquely mapping and all reads (including multi-mappers), respectively. The precise locations of all peaks are listed in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002911#pbio.3002911.s012" target="_blank">S1 Table</a>. The colored cytoband at the bottom of the plot shows the repeat organization. The color code is shown in the legend at the bottom of the figure. The data underlying this figure can be found at <a href="https://doi.org/10.5061/dryad.1zcrjdg2g" target="_blank">https://doi.org/10.5061/dryad.1zcrjdg2g</a> [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002911#pbio.3002911.ref040" target="_blank">40</a>].</p> <p>(PDF)</p>