S4 Fig - Encounter rates and engagement times limit the transmission of conjugative plasmids

<b>A)</b> Results from stochastic simulations showing the conjugation frequency (T/D, y axis) against time (min, x axis) obtained at different cellular densities (D). Shadowed areas correspond to 1 and 2 generation times. <b>B)</b> Comparison between computational simulations (dots) and theoretical predictions (lines) for the conjugation frequency (x axis, T/D) obtained at different cellular densities (x axis), at different generation times (legend). The normalized estimation error obtained at different generation times is shown in the inner graph. The normalized estimation error was measured as the difference between the conjugation frequency computed and estimated, divided by the average of the two. <b>C)</b> Effect of growth differences between donor and transconjugant cells on the estimation of the conjugation frequency. Computed (dots) and predicted (line) conjugation frequencies (x axis, T/D) obtained at different cell concentrations (x axis), when the transconjugants experience a growth deficit with respect to the donor cells indicated in the legend. As shown in the figure, a significant deviation from the estimated values was observed only for growth deficits >50%. (TIFF)