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<p>Fig A. Detailed workflow chart describing both the mouse model and stages of analysis. Created with <a href="http://Biorender.com" target="_blank">Biorender.com</a>, Inkscape, Matplotlib.py, and Plotly.py. Fig B. Schematic of the minimum model for protein homeostasis applied to each protein Created with Inkscape, Matplotlib.py, and Plotly.py. Fig C. Abundance and turnover FCs for ontologies related to endolysosomal processes in A) E2vsE3 and B) E4vsE3 Created with Inkscape, Matplotlib.py, and Plotly.py. Fig D. Abundance and turnover FCs for ontologies related to mitochondrial components in A) E2vsE3 and B) E4vsE3 Created with Inkscape, Matplotlib.py, and Plotly.py. Fig E. Abundance and turnover FCs for ontologies related to cellular metabolism in A) E2vsE3 and B) E4vsE3 Created with Inkscape, Matplotlib.py, and Plotly.py. Fig F. Abundance and turnover FCs for ontologies related to protein degradation in A) E2vsE3 and B) E4vsE3 Created with Inkscape, Matplotlib.py, and Plotly.py. Fig G. Model for comparison of ApoE2-dependent changes between brain and liver. Created with <a href="http://Biorender.com/" target="_blank">Biorender.com</a> and Inkscape. Fig H. Model for comparison of ApoE4-dependent changes between brain and liver. Created with <a href="http://Biorender.com" target="_blank">Biorender.com</a> and Inkscape.</p> <p>(DOCX)</p>