Efficacy of gemstone spectral computed tomography in evaluating the differentiation degree of lung squamous cell carcinoma

Objective To investigate the value of gemstone spectral CT in evaluating the differentiation degree of lung squamous cell carcinoma. Methods A total of 86 patients with lung squamous cell carcinoma who were diagnosed and treated in Puyang People’s Hospital from February 2019 to February 2020 were enrolled as subjects, and according to the results of postope-rative pathological examination, they were divided into group A (poorly differentiated), group B (moderately differentiated), and group C (highly differentiated). These three groups were compared in terms of gemstone spectral CT imaging parameters and di-sease conditions in the venous and arterial phases. The receiver operating characteristic (ROC) curve was plotted to investigate the efficacy of various gemstone spectral CT imaging parameters in assessing the differentiation degree of lung squamous cell carcinoma. Results There were no significant differences in gemstone spectral CT imaging parameters in the venous phase between groups (P>0.05). Compared with group C, groups A and B had significantly lower gemstone spectral CT imaging parameters of iodine concentration (IC), normalized iodine concentration (NIC), slope K value and effective atomic coefficient in the arterial phase, and group A had significantly lower parameters than group B (t=2.322-14.746,P<0.05). The ROC curve analysis showed that the combination of IC, NIC, slope K value, and effective atomic coefficient had the highest specificity and area under the ROC curve in evaluating the differentiation degree of lung squamous cell carcinoma. Conclusion The parameters of gemstone spectral CT have a relatively high value in assessing the differentiation degree of arterial-phase lung squamous cell carcinoma.