Ozonolysis\nwith MnO<sub>2</sub>: A Safe and Cost-Efficient\nWay for Producing Aldehydes and Ketones

Ozonolysis is a highly promising reaction for biomass\nvalorization\ndue to high efficiency, value-added carbonyl products, cheap oxidant,\nand mild conditions. However, the generation and accumulation of explosive\nperoxides during ozonolysis can be a risk and obstacle for large application.\nHerein, we propose a simple method that treats ozonolysis products\nwith MnO<sub>2</sub> to decompose and reduce the complex peroxides.\nHere, 60–90% peroxides can be removed within minutes at ambient\nconditions. Solvent and substrate structures influence MnO<sub>2</sub> activity. We further propose a novel in situ MnO<sub>2</sub>-assisted\nozonolysis, which restrains formation of peroxides while promotes\naldehydes formation. Kinetic investigations indicated that H<sub>2</sub>O<sub>2</sub> decomposition at low concentration is a first-order\nreaction, while it accelerated at high concentration due to an involvement\nof second-order decomposition of an organic peroxide generated in\na rapid equilibrium with H<sub>2</sub>O<sub>2</sub> and aldehyde.\nThis work suggests that ozonolysis enables greener biomass valorization\nwith more sustainable carbonyl products.