Clinical efficacy of laparoscopic peritoneal vaginoplasty in the treatment of MRKH syndrome

Objective To investigate the clinical efficacy of laparoscopic peritoneal vaginoplasty (Luohu Type II) in the treatment of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. Methods A retrospective analysis was conducted on the clinical data of 221 patients with MRKH syndrome treated at the Third Affiliated Hospital of Shenzhen University (Shenzhen Luohu People's Hospital) between January 2020 and April 2024.The patients were aged between 17 and 35 years, with an average age of (22±8) years. All patients underwent laparoscopic peritoneal vaginoplasty (Luohu Type II). Surgical time, hospital stay, intraoperative blood loss, and postoperative clinical outcomes were analyzed. Results All 221 patients in this group successfully underwent laparoscopic peritoneal vaginoplasty. The surgical time ranged from 25 to 100 minutes, with an average of (35±23) minutes. The hospital stay ranged from 15 to 29 days, with an average of (20±5) days. Intraoperative blood loss was between 10 and 100 mL. The preoperative vaginal indentation depth was 0.5 to 3 cm, and postoperative vaginal depth was (10±2) cm. The difference was statistically significant (P<0.05).All 221 patients successfully completed surgery and recovered well postoperatively.One patient experienced bladder injury and one patient had rectal injury, both of which were repaired with primary sutures.All patients were followed up for 1 to 37 months.Conclusion Laparoscopic peritoneal vaginoplasty (Luohu Type Ⅱ) is a reliable and effective surgical technique for the treatment of congenital absence of the vagina caused by MRKH syndrome, offering advantages such as minimal trauma,quick recovery,definite efficacy,and low complication rates.