Electrochemical\nSynthesis of 3‑(Sulfonyl)quinol-4-ones\nfrom <i>o</i>‑Alkynyl‑<i>N</i>‑(formyl)anilides\nand Sulfinates

Electrolysis of <i>o</i>-alkynyl-<i>N</i>-(formyl)anilides\nand sodium sulfinates on graphite electrodes delivers biologically\nsound 3-(sulfonyl)quinol-4-ones with moderate to good yields. The\nreaction is carried out in an undivided cell in the presence of silver(I)\noxide with potassium iodide or sodium tetrafluoroborate as the supporting\nelectrolyte. The reaction tolerates variously substituted anilides\nas well as aryl and alkyl sulfinates. The transformation proceeds\nas a domino sequence of oxysulfonylation and cyclocondensation steps.