Compact Plasma Ionization\nfor Ion Mobility Spectrometry\nUsing a 4.3 MHz Miniature Tesla Coil

In\nthis study, a low-cost 4.3 MHz plasma ionization source for\nion mobility spectrometry (IMS), utilizing a miniaturized Tesla coil,\nis presented. This compact design, combined with a 3D printed cyclic\nolefin copolymer (COC) housing, delivers a stable and directed plasma\nsuitable for ionization in IMS applications. The 3D printed housing\nensures chemical resistance and low off-gassing, which are crucial\nfor maintaining sample integrity. The Tesla coil produces a consistent\nsine wave at 4.3 MHz, and when connected to stainless steel screw\nelectrodes it generates a stable plasma capable of ionizing analytes\nsuch as limonene, MTBE, nicotine, 2-octanone, and propofol. Measurements\nwere conducted in both positive and negative ion modes. The results\ndemonstrate the Tesla coil’s effectiveness as a low-cost and\nreliable ionization source for IMS, offering comparable performance\nto traditional Ni<sup>63</sup> β-emitters. This advancement\nin plasma ionization technology could facilitate more accessible and\nflexible IMS systems for diverse analytical applications. The integration\nof 3D printing in the development of this ionization source underscores\nthe potential for customized, low-cost analytical instrumentation,\npromoting innovation in laboratory environments and commercial applications.