Enhanced Deoxygenation\nof Solvents via an Improved\nInert Gas Bubbling Method with a Ventilation Pathway

We introduce an improved\ninert gas bubbling method for\nsolvent\ndeoxygenation, featuring a ventilation path alongside the inert gas\ninlet to enhance the efficiency and reproducibility. While essential\nfor life, oxygen’s reactivity can disrupt scientific and industrial\nprocesses by forming unwanted intermediates and deactivating catalysts,\nnecessitating efficient deoxygenation methods. Traditional methods\nlike freeze–pump–thaw (FPT) are effective but time-consuming,\nrequire stringent safety measures, and have potential limitations\nfor use with aqueous and biological samples. Our enhanced inert gas\nbubbling method retains the simplicity and safety of conventional\nbubbling while achieving FPT-like deoxygenation efficiency, demonstrated\nby photoluminescence intensity and lifetime measurements in acetonitrile\n(ACN) and toluene (TOL). Simulations using a simplified kinetic model\nand the Stern–Volmer equation reveal that the added ventilation\npathway reduces oxygen contamination in Ar gas bubbles, improving\nthe deoxygenation efficiency. This method is widely applicable in\nacademic and industrial fields, requiring consistent and efficient\nsolvent deoxygenation.