Determination of the residual efficacy of broflanilide (VECTRON™ T500) insecticide for indoor residual spraying in a semi-field setting in Ethiopia

The rotational use of insecticides with diverse modes of action in indoor residual spraying (IRS) is pivotal for enhancing malaria vector control and addressing insecticide resistance. A key factor in national malaria vector control/elimination programmes is the rate at which these insecticides decay. VECTRON™ T500, with broflanilide as its active ingredient, is a recently developed candidate insecticide formulation which has shown promising results in certain phase II experimental hut trials. However, its residual efficacy across different settings has not been thoroughly investigated. This study evaluated the efficacy of VECTRON™ T500 on various wall surfaces (mud, dung, paint, and cement) and assessed its decay rates over time in Ethiopia.